The Early Neuropsychological and Behavioral Characteristics of Frontotemporal Dementia |
| |
Authors: | Dana Wittenberg Katherine L Possin Katya Rascovsky Katherine P Rankin Bruce L Miller Joel H Kramer |
| |
Institution: | (1) Memory and Aging Center, University of California—San Francisco Medical Center, San Francisco, CA, USA |
| |
Abstract: | Frontotemporal lobar degeneration (FTLD) represent a constellation of disorders that may be overlooked or misdiagnosed, despite
being fairly common presenile neurodegenerative diseases. Although the cognitive disorder can be difficult to document, particularly
early in the dementia course, neuropsychological evaluation can assist in the diagnosis. Neuropsychologists are in an excellent
position to draw from related disciplines like personality theory and social psychology to better assess the types of changes
that characterize the prodromal and early phases of the disease. This review summarizes the current state of the field in
the diagnosis of FTLD and discusses the emerging role of neuropsychology in elucidating the brain organization of complex
processes including empathy, behavioral control and inhibition, reward systems, appetitive behaviors, emotional regulation,
and goal-orientation. As this review underscores, frontotemporal dementia remains a powerful model for studying brain–behavior
relationships. |
| |
Keywords: | Frontotemporal dementia FTD Neuropsychology Differential diagnosis Executive function |
本文献已被 PubMed SpringerLink 等数据库收录! |
|