| 替代指标在心血管疾病临床决策中的正确认识 |
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| 引用本文： | 黄贤圣 赵水平 贺达仁 骆杨平. 替代指标在心血管疾病临床决策中的正确认识[J]. 医学与哲学(人文社会医学版), 2007, 28(4): 7-8 |
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| 作者姓名： | 黄贤圣 赵水平 贺达仁 骆杨平 |
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| 作者单位： | 中南大学湘雅二医院心内科 湖南长沙410011(黄贤圣，赵水平，骆杨平)，中南大学哲学系 湖南长沙410078(贺达仁) |
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| 摘 要： | 在心血管疾病临床试验中,替代指标常用于评价干预措施的疗效。但替代指标在心血管疾病临床试验中非常复杂,因此,心血管医生在解读和评价心血管疾病临床试验的结果时,应正确认识替代指标的内涵、应用背景及其局限性,同时,还应客观地评价相关替代指标的证据强度,以寻找最好的医学证据指导其临床决策和实践。
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| 关 键 词： | 替代指标 心血管疾病 决策 认识 |
| 文章编号： | 1002-0772（2007）04-0007-02 |
| 修稿时间： | 2006-11-20 |
The Correct Cognition about Surrogate End - points During Clinical Decision Making for Cardio-vascular Diseases |
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| HUANG Xian-sheng , ZHAO Shui-ping , HE Da-ren , et al,. The Correct Cognition about Surrogate End - points During Clinical Decision Making for Cardio-vascular Diseases[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2007, 28(4): 7-8 |
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| Authors: | HUANG Xian-sheng ZHAO Shui-ping HE Da-ren et al |
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| Affiliation: | Department of cardiovascular disease, Second Xiangya Hospital, Central South University, Changsha 410011,China |
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| Abstract: | A surrogate end-point is usually utilized to evaluate the therapeutic effects of some intervention in cardiovascular clinical trials. When a cardiologist readouts and evaluates the results from cardiovascular clinical trials, it is necessary that he should has a correct cognition about the connotation,background and limitation of surrogate end-points. At the same time, he should objectively evaluate the evidential efficacy of surrogate end-points involved. Only in this way, it is possible for a cardiologist to find the best medical evidence for his clinical decision and practice. |
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| Keywords: | surrogate end-point cardiovascular disease decision making cognition |
| 本文献已被 CNKI 维普 等数据库收录！ |
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