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肿瘤疫苗治疗肿瘤的前景
引用本文:张丽,孙原,吕鹏,吕申.肿瘤疫苗治疗肿瘤的前景[J].医学与哲学,2007,28(6):62-63.
作者姓名:张丽  孙原  吕鹏  吕申
作者单位:大连医科大学病原学实验室 辽宁大连116027(张丽,孙原),大连医科大学附属二院实验中心 辽宁大连116023(吕鹏,吕申)
摘    要:肿瘤疫苗的发展已经历了一个多世纪,20世纪50年代,人们开始了自体肿瘤疫苗的研究.使肿瘤疫苗(主动性免疫治疗)成为继手术、放疗、化疗之后的肿瘤治疗方法.肿瘤疫苗作为主动特异性免疫治疗,在临床中起到越来越重要的作用,人们开始尝试利用多种方法制备肿瘤疫苗并利用其促进机体免疫应答,从整体细胞,分子水平调控机体对肿瘤的免疫.目前肿瘤疫苗的研制已取得很大进展,给人类战胜肿瘤提供很大希望。

关 键 词:肿瘤疫苗  主动免疫  肿瘤抗原  免疫应答
文章编号:1002-0772(2007)06-0062-02
修稿时间:2007-04-172007-05-23

Promise of Tumor Vaccine in the Treatment of Neoplasm
ZHANG Li , SUN Yuan , LV Peng ,et al..Promise of Tumor Vaccine in the Treatment of Neoplasm[J].Medicine & Philosophy:Humanistic & Social Medicine Edition,2007,28(6):62-63.
Authors:ZHANG Li  SUN Yuan  LV Peng  
Institution:Dalian Medical University , Dalian 116027,China
Abstract:More than one century has been past since the start of tumor vaccine research. From the 1950s, autologous tumor vaccine was developed. This autonomous immune strategy then became an adjuvant therapeutic approach of surgery, radiotherapy and chemotherapy, and was widely used in clinical practice. Many attempts have been paid to generate tumor vaccines so as to enhance the immune response in systemic, cellular and molecular levels. The recent advance in cancer vaccines may provide new promise in cancer campaign.
Keywords:tumor vaccine  active immunotherapy  tumor antigens  immune response
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