幽门螺杆菌感染与上胃肠道疾病

幽门螺杆菌感染是消化性溃疡、胃MALT淋巴瘤和慢性胃炎的主要或重要病因,可能参与功能性消化不良的发病。根除幽门螺杆菌:(1)促进消化性溃疡愈合、预防溃疡复发;(2)可消除慢性胃炎胃黏膜活动性炎症,预防胃黏膜癌前变化发生、发展,并在一定程度上消除消化不良症状;(3)是早期胃MALT淋巴瘤首选治疗方法;(4)对功能性消化不良的治疗存在成本-效益比优势。

H. pylori Infection and Upper Gastrointestinal Diseases

H.pylori infection plays the etiological or important roles in the pathogenesis of peptic ulcer, chronic gastritis and gastric MALT lymphoma, and may also be involved in the pathogenesis of functional dyspepsia. Eradication of H. pylori results in: (1) improving the healing of peptic ulcer and preventing its relapse; (2) eliminating the activity of chronic gastritis, preventing the occurrence and development of gastric precancerous changes, and reduce the dyspeptic symptoms in part of patients. Eradication of H. pylori is the first choice of treatment for early gastric MALT lymphoma, and is cost-effective for treatment of functional dyspepsia.