HPA-Axis Activation as a Key Moderator of Childhood Trauma Exposure and Adolescent Mental Health |
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Authors: | Kate R Kuhlman Elisa G Geiss Ivan Vargas Nestor Lopez-Duran |
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Institution: | 1.Department of Psychology,University of California Los Angeles,Los Angeles,USA;2.Department of Social Science,Olivet College,Olivet,USA;3.Perelman School of Medicine,University of Pennsylvania,Philadelphia,USA;4.Department of Psychology,University of Michigan,Ann Arbor,USA |
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Abstract: | Individual differences in a child’s sensitivity to stress may influence whether youth exposed to trauma develop symptoms of psychopathology. We examined the interaction between HPA-axis reactivity to an acute stressor and exposure to different types of childhood trauma as predictors of mental health symptoms in a sample of youth. Youth (n?=?121, ages 9–16; 47% female) completed a standardized stress task, including 5 post-stress salivary cortisol samples. Parents also completed the Child Behavior Checklist as a measure of child internalizing and externalizing symptoms in the past month, and completed the Early Trauma Inventory (ETI) as a measure of their child’s trauma exposure. More emotional abuse and non-intentional trauma were associated with greater internalizing symptoms. Youth exposed to physical abuse who demonstrated slower HPA-axis reactivity had elevated internalizing and externalizing symptoms. Youth exposed to emotional abuse or non-intentional traumatic events who demonstrated faster HPA-axis reactivity had elevated internalizing and externalizing symptoms. Profiles of exaggerated or attenuated HPA-axis reactivity to acute stress may be risk factors for psychopathology in children facing different stressful social environments. |
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