The immunoenhancing effects of humor on secretory IgA and resistance to respiratory infections

Abstract

In three different studies involving exposun to two differcot humorous and comparison videotapes, it was demonstrated that humor arousal signiticantly increases S-IgA in college students. Furthermore significantly more of the subjects exposed to the humor films showed an increese in S-IgA than the subjects exposed to the comparison films. A good sense of humor, measured as a trait, was associated with higher baseline concentrations of S-IgA and with greater increases in S-IgA in response to a humor arousing film. Higher bascline kvels and gains in S-IgA in respoase to humor were associated with lower reported severity of colds in the past twelve months and in the three months following assessment. However, a good sense of humor was related to lesser cold incidence and severity only if it involved appreciation rather than production of humor. While those who actively tell jokes also show higher S-IgA levels, they show greater susceptibility to colds than those who only appreciate humor probably because they sodalize more often under conditions that expose them more to cold infections.