慢性军事应激致军人海马形态、认知功能和应对方式的变化

通过对572名连续4~16个月高强度军事训练的军人进行SCL-90测评, 研究慢性军事应激条件下军人海马形态、认知、心理特质和特质应对方式的变化特征。将其中l7例焦虑因子分≥3分者(焦虑或伴焦虑)设为研究组(A), 并以匹配法设对照组(B)。检测两组军人血皮质醇, 并用MRI观察海马形态、检测简单和复杂认知作业功能、以STAI测评状态-特质焦虑及以CCSQ测评应对方式, 探讨两组对应变化。研究结果显示：(1)血皮质醇：A、B组均高于正常水平, 有差异显著, A组显著高于B组。(2)海马形态：A组与B组MRI海马形态标准化后, A组海马形态显著萎缩, 与B组相比有显著性差异, 但各组每个同体的左右两侧之间相比无显著性差异。(3)认知作业功能：A组简单认知作业成绩与B组无显著差异, 但复杂认知作业成绩与B组相比有显著性差异。(4)状态-特质焦虑：A组的状态焦虑、特质焦虑分别与B组和常模比较均有显著变化, B组与常模相比状态焦虑变化显著, 特质焦虑变化不显著。(5)应对方式：A组积极应对方式平均值低于B组和常模并有显著性差异, B组高于常模; A组消极应对方式平均值高于B组和常模且有非常显著性差异, B组与常模无显著改变。结论 在慢性军事应激条件下, 特质焦虑个体的海马形态出现双侧萎缩, 复杂认知功能下降, 更易发生状态焦虑, 行为取向表现出积极应对方式降低、消极应对方式增加。

Changes in Hippocampus Morphology,Cognitive Function and Coping Style Induced by Chronic Military Stress

Many organic functions will be changed undergoing chronic strong stress,especially in the continuous activation of the HPA axis,which results in successive high level of glucocorticoid in blood.Afterward it will make hippocampal neurons become atrophic and cognitive function impairment,which has been confirmed in laboratory.This investigation studied the morphological changes of hippocampus,cognitive functions and coping styles undergoing the chronic military stress.The present investigation was intended pr...