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| 抑郁症的内表现型:快感缺失及其测量方法 | |
| 引用本文： | 刘文华,陈楚侨,黄敏.抑郁症的内表现型:快感缺失及其测量方法[J].心理科学进展,2010,18(2):271-281. |
| 作者姓名： | 刘文华 陈楚侨 黄敏 |
| 作者单位： | 1. 广州医学院人文社会科学学院应用心理学系,广州,510182;中山大学生命科学学院,广州,510275 2. 中国科学院心理研究所,心理健康院重点实验室,神经心理与应用认知科学实验室,北京,100101 3. 中山大学教育学院心理学系,广州,510275 |
| 基金项目： | 中国科学院心理研究所百人计划(O7CX031003); 中国科学院知识创新工程(KSCX2-YW-R-131); 中山大学百人计划(16000-3253182)资助项目 |
| 摘 要： | 快感缺失,指的是体验快乐的能力下降,广泛出现在抑郁症中,但同时也是其他如精神分裂症的重要症状。虽然快感缺失在精神病理学上非常重要,但较少受到研究重视。文章探讨了抑郁症和快感缺失的关系以及快感缺失个体的大脑奖励系统受损的神经机制,同时介绍了快感缺失可以进一步区分为期待性和消费性两种损害类型以及研究所用的主客观测量方法。指出快感缺失作为抑郁症最有可能的内表现型及其对疾病发展的作用,需要进一步研究深入。 |
| 关 键 词： | 快感缺失 抑郁症 神经基础 大脑奖励系统 测量 |
| 收稿时间： | 2009-10-30 |
Endophenotype of Depression: Anhedonia and Its Measurements |
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| LIU Wen-Hua,CHAN Raymond C. K.,HUANG Min-Er.Endophenotype of Depression: Anhedonia and Its Measurements[J].Advances In Psychological Science,2010,18(2):271-281. | |
| Authors: | LIU Wen-Hua CHAN Raymond C K HUANG Min-Er |
| Institution: | LIU Wen-Hua1,2,CHAN Raymond C. K.3,HUANG Min-Er4 (1Department of Applied Psychology,Faculty of Humanities , Social Sciences,Guangzhou Medical College,Guangzhou 510182,China) (2Faculty of Life Sciences,Sun Yat-Sen University,Guangzhou 510275) (3Neuropsychology , Applied Cognitive Neuroscience Laboratory,Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China) (4Department of Psychology,Guangzhou 510275,China) |
| Abstract: | Anhedonia is defined as the diminished capacity to experience pleasure,which is widely recognized to occur in depression,and is a prominent feature that is involved in several types of psychiatric disorders and maladaptive behaviors. Although anhedonia is regarded as an important symptom in psychopathology,it has received relatively little attention. To better understand the role of anhedonia in depression,this paper reviews the relationship between depression and anhedonia,and the neural substrates of anhe... |
| Keywords: | anhedonia depression neural substrate brain reward system measurement |
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