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Early Adolescent Growth in Depression and Conduct Problem Symptoms as Predictors of Later Substance Use Impairment
Authors:Carolyn A. McCarty  Brian T. Wymbs  W. Alex Mason  Kevin M. King  Elizabeth McCauley  John Baer  Ann Vander Stoep
Affiliation:1. Center for Child Health, Behavior, and Development, University of Washington and Seattle Children’s Hospital, M/S: CW8-6, P. O. Box 5371, Seattle, WA, 98145, USA
2. Department of Psychology, Ohio University, 200 Porter Hall, Athens, OH, 45701-2979, USA
3. Boys Town National Research Institute for Child and Family Studies, 14100 Crawford Street, Boys Town, NE, 68010, USA
4. Psychology Department, University of Washington, P. O. Box 351525, Seattle, WA, 98108, USA
5. University of Washington and Seattle Children’s Hospital, M/S: W-3636, 4800 Sand Point Way NE, Seattle, WA, 98105, USA
6. VA Medical Center, Box 358280 – S116 – ATC, 1660 S. Columbian Way, Seattle, WA, 98108, USA
7. University of Washington, 6200 NE 74th Street, Suite 110, Seattle, WA, 98115, USA
Abstract:Most studies of adolescent substance use and psychological comorbidity have examined the contributions of conduct problems and depressive symptoms measured only at particular points-in-time. Yet, during adolescence, risk factors such as conduct problems and depression exist within a developmental context, and vary over time. Though internalizing and comorbid pathways to substance use have been theorized (Hussong et al. Psychology of Addictive Behaviors 25:390-404, 2011), the degree to which developmental increases in depressive symptoms and conduct problems elevate risk for substance use impairment among adolescents, in either an additive or potentially a synergistic fashion, is unclear. Using a school-based sample of 521 adolescents, we tested additive and synergistic influences of changes in depressive symptoms and conduct problems from 6th to 9th grade using parallel process growth curve modeling with latent interactions in the prediction of late adolescent (12th grade) substance use impairment, while examining gender as a moderator. We found that the interaction between growth in depression and conduct disorder symptoms uniquely predicted later substance use problems, in addition to main effects of each, across boys and girls. Results indicated that adolescents whose parents reported increases in both depression and conduct disorder symptoms from 6th to 9th grade reported the most substance use-related impairment in 12th grade. The current study demonstrates that patterns of depression and conduct problems (e.g., growth vs. decreasing) are likely more important than the static levels at any particular point-in-time in relation to substance use risk.
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