兴奋性氨基酸对猫怒叫反应的影响

为了提供猫“怒叫中枢”的神经元胞体参与怒叫反应的直接证据,本实验观察了“怒叫中枢”内注射谷氨酸单钠和海人酸对猫怒叫反应的影响。结果表明,“怒叫中抠”内注射谷氨酸单钠后,动物的呼吸加快,瞳孔明显扩大,电刺激引起叫反应的阈值明显降低。注射海人酸也可引起呼吸加快,瞳孔扩大,电刺激引起叫反应的阈值明显下降等反应。实验所用的动物中有3只动物,海人酸还可直接诱发叫反应。本实验提示,电刺激“怒叫中枢”引起的怒叫反应是神经元胞体兴奋的结果,而不是过路纤维兴奋的作用。

THE EFFECT OF EXCITATORY AMINO ACIDS ON GROANING RESPONSES IN CATS

In order to investigate the vocalization mechanism of the "groa-ning center" in cats, we studied the effect of microinjection of glu-tamate and kainic acid into the "groaning center"on groaning respon-ses. It was found that the respiratory rate increased markedly andthe pupils of cats dilated immediately after injection. Furthermore,the threshold of groaning responses induced by electrical stimulationreduced significantly after injection. In some cats, it was also obser-ved that groaning responses could be directly induced by kainicacid. Our results suggested that the vocalization elicited by electricalstimulation of the "groaning center" represent responses due to theactivation of neuronal cell bodies.