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Cognition and survival in a biracial urban population of old people
Authors:Robert S. Wilson   Lisa L. Barnes   Carlos F. Mendes de Leon  Denis A. Evans  
Affiliation:1. Rush Alzheimer''s Disease Center (RSW, LLB), Rush University Medical Center, Chicago, IL, United States;2. Rush Institute for Healthy Aging (CFMDL, DAE), Rush University Medical Center, Chicago, IL, United States;3. Department of Neurological Sciences (RSW, LLB, DAE), Rush University Medical Center, Chicago, IL, United States;4. Department of Behavioral Sciences (RSW, LLB), Rush University Medical Center, Chicago, IL, United States;5. Department of Internal Medicine (CFMdL, DAE), Rush University Medical Center, Chicago, IL, United States;1. University of Miami Center on Aging, Miami, FL;2. Dartmouth Centers for Health and Aging, Geisel School of Medicine at Dartmouth, Hanover, NH;3. NIMH Center for Late Life Depression Prevention and Treatment, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, PA;4. Center for Multicultural Mental Health Research, Cambridge Health Alliance, Somerville, MA;5. Center for Health Equity, School of Public Health, University of Maryland, College Park, MD;1. Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL;2. Rush Alzheimer''s Disease Center, Rush University Medical Center, Chicago, IL;3. Department of Neurological Sciences, Rush University Medical Center, Chicago, IL;4. Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL;5. Center on Aging and Health, Department of Medicine, Johns Hopkins University, Baltimore, MD;6. Department of Epidemiology, University of Michigan, Ann Arbor, MI;1. Department of Microbiology (VIA, RS), Department of Ear, Nose, and Throat (DRS), Mathikere Sampangi Ramaiah Medical College, Bangalore, Karnataka, India;1. Dept. Optometry and Vision Science, University of Alabama at Birmingham (UAB), Birmingham, AL, USA;2. HSF Neurology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA;3. Dept. Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA;4. Dept. Psychiatry, Vanderbilt University, Nashville, TN, USA;1. Faculty of Psychology, University of Geneva, Switzerland;2. Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Denmark;3. Department of Scandinavian Studies and Linguistics, University of Copenhagen, Denmark;4. CerCA (UMR 7295), University of Poitiers, France
Abstract:We examined the relation of level of cognition to survival in a biracial community population of more than 10,000 older persons. At baseline, participants completed 4 cognitive tests from which a composite global cognitive measure was derived. During up to 14 years of follow-up (mean = 6.9 years), 4201 people died (41.6%). Higher level of cognitive function was associated with increased survival even after controlling for health related and lifestyle variables. The association did not differ between African Americans and whites; it was stronger in older than younger persons; and it was especially pronounced for perceptual speed. The results underscore the importance of cognition to survival in old age.
Keywords:Cognition   Mortality   Population studies   Race   Perceptual speed
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