The lowering of bilirubin levels in patients with neonatal jaundice using massage therapy: A randomized,double-blind clinical trial |
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| Institution: | 1. Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran;2. Department of Biostatistics and Epidemiology, Hamadan University of Medical Sciences, Hamadan, Iran;1. Department of Dynamic and Clinical Psychology, Sapienza University, Rome, Italy;2. Department of Anesthesiology and Intensive Care, UCSC, Rome, Italy;1. College of Nursing and Health Sciences, Florida International University, Miami, FL, USA;2. External IMPEP Study Co-Investigator, University of Miami, Miami, FL, USA;3. Department of Health Promotion and Disease Prevention, Robert Stemple School of Public Health, Florida International University, Miami, FL, USA;4. Memorial Regional Hospital, Hollywood, FL, USA;5. AIDS Healthcare Foundation, Miami Beach, FL, USA;6. IMPEP Study Team, Robert Stemple School of Public Health, Florida International University, Miami, FL, USA;1. Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia;2. Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia;3. Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia;4. Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia;1. Touch Research Institute, University of Miami/Miller School of Medicine, United States;2. Fielding Graduate University, United States;3. The Children’s Hospital of Philadelphia, Saint Joseph’s University, United States;1. Brazilian Academic Consortium for Integrative Health (CABSIn), Brazil;2. Latin American and Caribbean Center on Health Sciences Information BIREME - PAHO – WHO, Brazil;3. Departamento de Medicina Preventiva, Escola Paulista de Medicina, Universidade Federal de São Paulo-Unifesp, Brazil |
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| Abstract: | ObjectiveDue to the effects of massage on various laboratory parameters (including those related to jaundice) in infants and the expansion of existing studies to achieve effective and safe therapy in the treatment of neonatal jaundice, this study aimed to investigate the effect of massage on bilirubin levels in cases of neonatal jaundice.MethodsIn this study, 134 patients were randomly assigned to either an intervention group (massage combined with phototherapy, n = 67) or a control group (phototherapy only, n = 67). In both groups, serum total bilirubin level and frequency of daily bowel movements were measured and compared during each of the first four days of treatment.ResultsBaseline levels of bilirubin were similar between the two groups (P > 0.05). During the measurements obtained post-intervention, significant differences surfaces between the two groups in bilirubin levels and frequency of daily bowel movements (P < 0.05 for both). No significant relationship was observed during days 1 and 2 of massage therapy between daily frequency of bowel movements and serum bilirubin level (P > 0.05); this relationship became significant during the third and fourth days (P < 0.05).ConclusionMassage therapy combined with phototherapy is an effective method for reducing serum total bilirubin in infants with neonatal jaundice. |
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| Keywords: | Neonatal jaundice Massage therapy Phototherapy Pediatrics Billirubin |
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