| HBeAg阳性慢性乙型肝炎抗病毒治疗药物的比较 |
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| 引用本文： | 张文坚,谭德明,龚环宇.HBeAg阳性慢性乙型肝炎抗病毒治疗药物的比较[J].医学与哲学,2008,29(11):37-39. |
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| 作者姓名： | 张文坚 谭德明 龚环宇 |
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| 作者单位： | [1]中南大学湘雅三医院感染病科,湖南长沙410013 [2]中南大学湘雅医院感染病科,湖南长沙410008 |
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| 摘 要： | 抗病毒治疗是慢性乙型肝炎治疗的关键。目前抗乙型肝炎病毒（HBV）药物主要有两大类，本文从抗病毒治疗的适应症、禁忌症、治疗效果、耐药性、依从性和治疗费用等方面对现有抗HBV药物进行了比较和分析，认为在选择抗HBV药物时，应遵循规范化与个体化相结合的原则，在患者能承受的费用范围内，尽量选择抗病毒作用强、耐药率低、耐受性良好的药物。
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| 关 键 词： | 慢性乙型肝炎 抗病毒治疗 干扰素类 核苷(酸)类似物 |
Comparative Study on Anti--HBV Drugs in HBeAg Positive Chronic Hepatitis B |
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| Institution: | ZHANG Wen-jian , TAN De-ruing ,GONG Huan-yu. (Department of Infectious Disease, Third Xiangya Hospital, Central South University, Changsha 410013, China) |
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| Abstract: | Antiviral treatment is the key therapy of chronic hepatitis B. Currently there are two major types of approved anti --HBV drugs, and they are compared in the aspects of indications and contraindications of anti--HBV therapy, therapeu tic efficacy, drug resistance, compliance and expenditure in this paper. When we choose anti--HBV drugs, the principle of the combination of normalization and individualization should follow, and we should select the drug with strong antivirus effect, low resistance rate, and good tolerance. |
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| Keywords: | chronic hepatitis B antiviral treatment interferon nucleoside analogues |
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