| Abstract: | The development of feeding patterns was investigated in weanling rats and in rats with lateral hypothalamic lesions. From 16 to 25 days of age, the weanlings demonstrated a preprandial intake pattern, i.e., a positive correlation between meal size and time since the preceding meal. This subsequently declined while the postprandial relationship (correlation with time until subsequent meal) began to emerge such that by 30-35 days of age a full adult pattern was observed. Rats recovering from lateral hypothalamic lesions, for a brief period, also demonstrated a preprandial intake pattern. The postprandial relationship was abolished by the lesions. These results suggest that the development of adult meal patterning results from maturation of lateral hypothalamic mechanisms governing meal initiation. |
