Some aspects on behavioral teratology research

A compelling question in teratology research is whether the experimental model used allows for extrapolation from laboratory animals to man. Our thesis is that behaviors that are biologically relevant for the animal are more likely to reveal the relationship between the behavior and its substrate than are non-specific behaviors. Applying this reasoning to the study of the ontogenesis of the behavior, we plead for including the use of species-typical behaviors in testing for teratogenic effects. Our further discussion is focussed upon the different levels at which an analysis of teratogenic effects may be carried out. At one level, the analysis is directed towards the behavioral effects of a given treatment; at another level to specify the function that is impaired by the treatment.