Treatment consonance and response profiles in agoraphobia: the role of individual differences in cognitive, behavioral and physiological treatments |
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| Authors: | L Michelson |
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| Affiliation: | 1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China;2. Key Laboratory of Technologies and Applications of Ultrafine Granular Powder of Chinese Materia Medica, State Administration of Traditional Chinese Medicine, China;3. Departments of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China;4. Takarazuka University of Medical and Health Care, Hanayashiki-Midorigaoka, Takarazuka City, Japan;5. Dachpharm Development Co. Ltd, Jinan, China;1. Post-Graduate Program in Dental Science, Federal University of Santa Maria (UFSM), 1184 Floriano Peixoto, 7th floor, 97015-372, Santa Maria, RS, Brazil;2. Department of Biomaterials and Biomimetics, New York University, 433 First Avenue, 8th floor, 10010, New York, NY, USA;3. Department of Restorative Dentistry, Federal University of Santa Maria (UFSM), 1184 Floriano Peixoto Street, 3rd floor, 97015-372, Santa Maria, RS, Brazil;1. Florida State University, Tallahassee, FL, USA;2. University of Houston, Houston, TX, USA;3. University of Texas MD Anderson Cancer Center, Houston, TX, USA;1. Institute of Virology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany;2. Department of Medical Microbiology, Jos University Teaching Hospital, Jos, Nigeria;3. Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany;4. Biotechnology Department, National Veterinary Research Institute, Vom-Jos, Nigeria;5. Department of Medicine, Jos University Teaching Hospital, Jos, Nigeria;6. Department of Obstetrics and Gynaecology, Jos University Teaching Hospital, Jos, Nigeria;7. Department of Paediatrics, Jos University Teaching Hospital, Jos, Nigeria;8. University of Jos, Jos, Nigeria;9. University of Abuja, Abuja, Nigeria;10. Department of Paediatrics, Federal Medical Center, Keffi, Nigeria;1. Department of Psychiatry, University of Naples SUN, Largo Madonna Delle Grazie, 80138 Naples, Italy;2. Mental Health Centre of Grosseto, Italy;3. Mental Health Centre of Lanciano, Italy;4. Pavia University, Italy;5. Mental Health Centre of Montecatini, Italy;6. Mental Health Centre of Lanusei, Italy;7. Niguarda Hospital, Milan, Italy;8. Mental Health Centre of Sassuolo, Italy;9. Mental Health Centre of Foligno, Italy;10. Mental Health Centre of Rome, Italy;11. Mental Health Department of Campobasso, Italy;12. University College of London, UK |
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| Abstract: | The mediating role of individual differences, response profiles and treatment consonance in the outcome of agoraphobics undergoing cognitive, behavioral and physiological treatments was investigated. Severe and chronic agoraphobics (DSM-III) received either Paradoxical Intention, Graduated Exposure or Progressive Deep Muscle Relaxation Training consisting of 12 2-hr weekly sessions. An assessment battery was utilized consisting of ratings of severity, phobia, anxiety, depression and avoidance as well as direct measures of behavioral, cognitive and psychophysiological response systems which were evaluated at pre, mid, post and 3-month follow-up phases. Comparisons of Ss who were consonantly vs non-consonantly treated were conducted, based upon their initial response profiles. Significant differential treatment outcome and treatment × response profile interaction effects were observed. Hypotheses were confirmed regarding the predicted effects of consonant vs non-consonant Ss × treatment interactions. The short- and long-term implications of individual differences and treatment consonance in agoraphobia and anxiety disorders are discussed. Conceptual, methodological and clinical issues are highlighted with regard to both clinical intervention and future research. |
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