Abstract: | Individual variation in intermale aggression is to a significant degree based upon genetic variation, but environmental factors can also exert their influence on the level of aggression. Moreover, genotype–environment interactions are a well‐known phenomenon. In the present experiment, I tested whether cage size or handling during development had an influence on adult attack latency scores. To be able to study a genotype–environment interaction, mice from two bidirectionally on attack latency selected lines were used. The size of the cage in which the mice grew up had no long‐term effect on aggression, neither in the high‐ nor in the low‐aggressive line. Handling, however, significantly increased the adult aggression of males from the low‐aggressive line. Despite the differential effect of handling on genetically high‐ and low‐aggressive mice, handling was not able to undo the marked differences in attack latencies between mice from both lines. Aggr. Behav. 25:365–368, 1999. © 1999 Wiley‐Liss, Inc. |