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瘦素及其受体在消化道肿瘤研究中的应用
引用本文:华正祥 侯振江. 瘦素及其受体在消化道肿瘤研究中的应用[J]. 医学与哲学(人文社会医学版), 2007, 28(10): 50-51,66
作者姓名:华正祥 侯振江
作者单位:[1]承德医学院附属医院检验科,河北承德067000 [2]沧州医学高等专科学校,河北沧州061001
基金项目:河北省科学技术发展和规划项目:(No.052761288)
摘    要:瘦素是肥胖肥胖基因编码的产物,与其受体结合发挥其生物学作用。具有促进细胞增殖分化、增加细胞侵袭性、促进血管形成和调节机体免疫等作用。流行病学调查和基础研究证实,Leptin与肿瘤的发生密切相关,肿瘤的发生、发展和转归在很大程度上依赖于新生血管的形成。本文综述了瘦素及其受体在消化道肿瘤研究中的进展。

关 键 词:瘦素 瘦素受体 消化道肿瘤
文章编号:1002-0772(2007)10-0050-03
修稿时间:2006-12-072007-09-16

Progress of Leptin and Its Receptor in Digestive Tract Tumor
HUA Zheng-xiang, HOU Zhen-jiang. Progress of Leptin and Its Receptor in Digestive Tract Tumor[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2007, 28(10): 50-51,66
Authors:HUA Zheng-xiang   HOU Zhen-jiang
Affiliation:Department of Clinical Laboratory of Affiliated Hospital Medical College, Chengde 067000, China
Abstract:Leptin is an expression from fattness gene in fat cells, which combines with its acceptor to indicate its biological function, to promote cell division, agression and to form blood tube and to regulate immune system. Epidemiological research and basic study have proved that Leptin is closely related to tumors, happening, development and termination of tumors is decided on forming of new bolld vessels. This article is to discuss new development about Leptin and its acceptor in digestive tumors.
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