A biometrical study of schizotypy in a normal population |
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| Institution: | 1. Translational Research Center, University Hospital of Psychiatry and Psychotherapy, University of Bern, 3000 Bern 60, Switzerland;2. Orygen, The National Centre of Excellence in Youth Mental Health & Centre for Youth Mental Health, University of Melbourne, Parkville, VIC 3052, Australia;3. Institute for Psychiatry and Psychotherapy Bern, Waisenhausplatz 25, 3011 Bern, Switzerland;4. Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Zucker School of Medicine at Northwell/Hofstra, New York, NY, USA;1. Center for BrainHealth, The University of Texas at Dallas;2. Departments of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States;3. Departments of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States;4. Departments of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States;5. Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States |
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| Abstract: | A recently devised two-scale questionnaire (STQ) for measuring ‘borderline’ personality traits, together with the EPQ, was administered to 108 monozygotic and 102 dizygotic adult twin pairs. Initial item and scale analyses of the STQ indicated good internal consistency and acceptably high endorsement frequencies for individual items, as well as an absense of any marked skew in the scale distributions. The pattern of correlations with the EPQ closely resembled that seen in earlier, smaller-sized studies, the most notable feature being a positive correlation between the borderline scales and the N-scale. Biometrical analysis of the data suggested that, for the main STQ scale (‘schizotypal personality’), the best-fitting model was one assuming additive genetic variation combined with within-family environmental effects: results for the other (‘borderline personality’) scale were less clear cut. A number of sex differences were also observed: males had lower schizotypy scores than females, while the biometrical analysis suggested that schizotypy may be under greater genetic control in males than in females. The data are presented and discussed in the context of the dimensional/biological theory of disposition to psychosis. |
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