Longitudinal Intellectual Assessment of Children With HIV Infection |
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Authors: | Email author" target="_blank">Suzie?FranklinEmail author Hyun?J?Lim Kimberly?M?Rennie Dan?Eastwood Barbara?Cuene Peter?L?Havens |
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Institution: | (1) Children's Hospital of Wisconsin, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin, 53226;(2) Department of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin, 53226 |
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Abstract: | The objective of this paper was to describe the intellectual development of 39 children with HIV infection. The children received
serial evaluations over a 10-year period. Thirty-nine children were assessed with age-appropriate intellectual measures at
regular intervals as part of their treatment in the HIV Program of a children's hospital. Children showed an 24-point drop
in mean Bayley Mental scores over the first 2 years of life. McCarthy scores remained in the low average range from ages 3–5
years. IQ scores were stable by age 6 in the low average range, and unchanged through age 12. Significant changes in memory,
vocabulary, and performance subtests were noted. Children with HIV infection demonstrated a significant decline in mental
functioning over the first 2 years of life, fell into the low average range by age 3, and remained in the low average range,
with subtle changes in some areas. |
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Keywords: | children HIV disease IQ longitudinal assessment |
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