Non-pharmacologic Interventions for CFS: A Randomized Trial |
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Authors: | Leonard A Jason Susan Torres-Harding Fred Friedberg Katrina Corradi Mary Gloria Njoku Julie Donalek Nadia Reynolds Molly Brown Bing Bing Weitner Alfred Rademaker Morris Papernik |
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Institution: | (1) Center for Community Research, DePaul University, 990 W. Fullerton Ave., Chicago, IL 60614, USA;(2) Roosevelt University, Chicago, IL, USA;(3) Stony Brook University, Stony Brook, NY, USA;(4) Northwestern University, Chicago, IL, USA;(5) Rush University Medical Center, Chicago, IL, USA |
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Abstract: | Non-pharmacological behavioral treatments for CFS have been suggested as promising. These trials have tested protocols composed
of behavioral, cognitive and cognitive–behavioral interventions but there have been few efforts to differentially evaluate
their outcomes. The primary purpose of the current study was to evaluate the effectiveness of nurse delivered non-pharmacologic
interventions. In the present study, 114 participants diagnosed with CFS were randomly assigned to four 6-month interventions.
The interventions were: cognitive–behavior therapy, cognitive therapy, anaerobic activity, and a relaxation control group.
The study found that these interventions led to increases in several areas of functioning, with more consistent changes occurring
among those participants in the cognitive condition. For the 25 variables in this study, significant change occurred for 28%,
20%, 16%, and 12% of the variables for the cognitive, cognitive behavior therapy, anaerobic activity, and relaxation conditions,
respectively. However, the majority of participants continued to be diagnosed with CFS following the treatment trial. Implications
of these findings are discussed. |
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Keywords: | CFS ME Non-pharmacologic Treatment Trial Cognitive– behavior therapy |
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