Selective tuning of the right inferior frontal gyrus during target detection |
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Authors: | Adam Hampshire Russell Thompson John Duncan Adrian M Owen |
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Institution: | 1. MRC Cognition and Brain Sciences Clinic, Cambridge University, 15 Chaucer Road, CB2 7EF, Cambridge, England
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Abstract: | In the human brain, a network of frontal and parietal regions is commonly recruited during tasks that demand the deliberate,
focused control of thought and action. Previously, using a simple target detection task, we reported striking differences
in the selectivity of the BOLD response in anatomically distinct subregions of this network. In particular, it was observed
that the right inferior frontal gyrus (IFG) followed a tightly tuned function, selectively responding only to the current
target object. Here, we examine this functional specialization further, using adapted versions of our original task. Our results
demonstrate that the response of the right IFG to targets is a strong and replicable phenomenon. It occurs under increased
attentional load, when targets and distractors are equally frequent, and when controlling for inhibitory processes. These
findings support the hypothesis that the right IFG responds selectively to those items that are of the most relevance to the
currently intended task schema. |
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Keywords: | |
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