Cognitive activity and risk of alzheimer's disease |
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| Authors: | Robert S. Wilson David A. Bennett |
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| Affiliation: | Rush Alzheimer's Disease Center (R.S.W., D.A.B.) and Departments of Neurological Sciences (R.S.W., D.A.B.) and Psychology (R.S.W.), Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois |
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| Abstract: | Recent research suggests that frequent participation in cognitively stimulating activities may reduce risk of Alzheimer's disease in old age. We review epidemiological evidence of such an association. We then consider whether cognitive activity can account for the association between higher educational and occupational attainment and reduced risk of Alzheimer's disease. Finally, we discuss the behavioral and neurobiological mechanisms that may underlie the association between cognitive activity and risk of Alzheimer's disease. |
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| Keywords: | Alzheimer's disease cognitive activity longitudinal studies |
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