肿瘤转移形成中癌细胞与基质之间的辩证关系

人们认识肿瘤的内在本质主要是通过它的表面形式即病理生物学行为来进行的，但因客观条件的限制，对其瘤细胞的内在特性和瘤细胞与胞外基质相互影响的认识还有限。因为肿瘤细胞在浸润与转移过程中有时并非与间质的反应情况相平行。由此要求我们正确认识肿瘤浸润转移过程中的对立统一规律，揭示隐蔽在其内部联系的本质和外部表现。

Dialectic Relationship Between Cancer Cells and Extracellular Matrix in Metastasizing Progression

The main way to know the internal essence of cancer cells is through understanding cancer manifestation i.e.,its pathologically biological behavior.However,the relationship between cancer cells and extracellular matrix has not been completely understood up to date in view of the limited knowledge in that the invading and metastasizing progression of cancer cells is sometimes not paralleled to stroma reaction.So it needs to exactly find the antinomy and unification rules of the cancer invading and metastasizing and to discover cancer essence and outward expression.As molecular biology,etc.Penetrating to other disciplines these years,especially oncogene role in metastasis has gradually been recognized,it's necessary to organically combine the characterizes of the changeable stroma and cancer cells in order to completely understand the mechanism of cancer metastasis.