| 食管鳞癌患者高血小板血症与预后关系分析 |
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| 引用本文： | 许鹏,雷畅,张兆卿,张志平,王丹云,王宗明,沈令广,杨长征. 食管鳞癌患者高血小板血症与预后关系分析[J]. 医学与哲学(人文社会医学版), 2009, 0(8): 27-28,36 |
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| 作者姓名： | 许鹏 雷畅 张兆卿 张志平 王丹云 王宗明 沈令广 杨长征 |
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| 作者单位： | [1]山东大学附属济南市中心医院胸外科,山东济南250013 [2]山东省军区门诊部,山东济南250013 [3]章丘市人民医院胸心外科,山东章丘250200 |
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| 摘 要： | 探讨食管鳞癌患者高血小板血症与临床病理特征及预后的关系，回顾性分析340例食管鳞癌患者术前血小板计数，结果显示高血小板血症与肿瘤长度、分化程度、肿瘤分期及淋巴转移密切相关（P〈0．05），而与性别、年龄及肿瘤位置无关（P〉0．05）；高血小板血症者的生存率明显低于血小板计数正常者（P〈0．001）；并且高血小板血症是影响食管鳞癌患者预后的独立因素。因此高血小板血症与食管鳞癌的进展及不良预后有关。
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| 关 键 词： | 食管肿瘤 血小板增多 预后 |
The Prognostic Significance of Thrombocytosis in Patients with Esophageal Squamous Cell Carcinomas |
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| Affiliation: | XU Peng, LEI Chang, ZHANG Zhao- qing ,et al.( Department of Thoracic Surgery, Ji＇nan Central Hospital Affiliated to Shandong University, Ji＇nan 250013, China) |
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| Abstract: | To analyze the clinicopathologic significance and prognostic value of thrombocytosis in patients with esophageal squamous cell carcinomas,we retrospectively analyzed Platelet counts measured before surgery in 340 patients diagnosed with esophageal squamous cell carcinomas. Thrombocytosis in patients with esophageal squamous cell carcinomas was correlated to length of neoplasm, grade of differentiation, stage of tumors and lymphatic metastasis（P〈0.05）, but not with gender, age and tumor location（P〉0.05）. The overall survival rates in patients with thromboeytosis was significantly lower than that without thrombocytosis （P〈0.001）. Thrombocytosis was an independent prognostic factor. These results suggest that thromhocytosis is associated with tumor progression and poor survival in patients with esophageal earei noma. |
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| Keywords: | esophageal neoplasms thrombocytosis prognosis |
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