Abstract: | The present report reviews some findings of a 20-year longitudinal study of Danish children at risk for schizophrenia. Early factors predictive of later schizophrenia in high-risk children, including infant temperament and the effect of perinatal complications, are reviewed. In addition, the role of maternal absence as a stressor is examined. Findings related to sex differences in the vulnerability of high-risk children to later pathology are discussed. Possible interactions of these factors and maternal psychopathology are briefly explored. |