Psychological Factors that Link Socioeconomic Status to Depression/Anxiety in Patients with Systemic Lupus Erythematosus |
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| Authors: | Desiree R Azizoddin Geraldine Zamora-Racaza Sarah R Ormseth Lekeisha A Sumner Chelsie Cost Julia R Ayeroff Michael H Weisman Perry M Nicassio |
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| Institution: | 1.Department of Psychology,Loma Linda University,Loma Linda,USA;2.Department of Anesthesiology,Stanford University Medical Center,Palo Alto,USA;3.Division of Rheumatology,Cedars-Sinai Medical Center,Los Angeles,USA;4.Department of Medicine,University of the Philippines - Philippine General Hospital,Manila,Philippines;5.Department of Psychiatry and Biobehavioral Sciences,David Geffen School of Medicine at UCLA,Los Angeles,USA;6.Department of Psychiatry and Behavioral Neurosciences,Cedars-Sinai Medical Center,Los Angeles,USA;7.Pepperdine University,Malibu,USA;8.Postbaccalaureate Premedical Program,University of Southern California,Los Angeles,USA;9.Cousins Center for Psychoneuroimmunology,University of California Los Angeles,Los Angeles,USA |
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| Abstract: | Our analyses examined whether reserve capacity factors would explain the relationship between socioeconomic status (SES) and symptoms of depression/anxiety in patients with systemic lupus erythematosus (SLE). We assessed disease activity, depression/anxiety symptoms, and intrapersonal and interpersonal reserve capacity measures in 128 patients with SLE. Multiple meditational analyses revealed that intrapersonal and interpersonal psychosocial aspects of reserve capacity fully mediated the relationship between SES and depression/anxiety. Lower SES was indirectly associated with higher symptoms of depression and anxiety through the effects of psychosocial resilience. Interventions aimed at improving modifiable reserve capacity variables, such as self-esteem and optimism, may improve anxious/depressive symptomatology in patients with SLE. |
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