临床均势原则辨析——对临床科研方法的伦理思考

随机对照试验作为一种评价新疗法的可靠设计方法,开始逐渐被世界范围内的临床医生所广泛接受和采用,成为目前最重要的试验方法之一。RCT的运用应该遵循一定的伦理准则,即临床均势原则。围绕临床均势原则这一主题,对随机对照试验的方法论进行较为深入的伦理学思考。并对临床均势的内涵、伦理意义,以及这一伦理要求在实践中所引发的各种伦理争论加以探讨。

Analysis on Principle of Clinical Equipoise:ethical reflection on methodology of clinical research

As a reliable design method of evaluating new therapy, randomization clinical trial (RCT) is generally adopted by clinical researchers of the world, and becomes one of most important experimental method at present. The application of RCT shall obey to a certain ethical principle, that is, clinical equipoise.To provide relevantly deep ethical reflections on the methodology of RCT, focusing on principle of clinical equipoise and mainly explore the meaning and ethical significance of clinical equipoise, and various debates raised in the practices of the ethical principle.