The influence of the ganglionic blocking agent ganlion on viscerovisceral and viscerocerebral reactions of the cat

In 21 subacute or chronic cats the influence of gallbladder distention on heart rate, respiratory movements, bio-electrical activity of the cerebral cortex and motor behavior were studied under normal conditions and after intraperitoneal administration of a ganglionic blocking agent. In control groups without administration of the drug, changes of heart and respiratory rates were observed during the mechanical stimulation of the gallbladder. These effects were independent of a sleeping or non-sleeping state of the animal. In some cases viscerovisceral reactions could be accompanied by an arousal reaction. After administration of the blocking agent in amounts ranging between 5–50 mg/kg body wt the viscerovisceral reactions were inhibited, whereas the behavioral arousal remained.