An adaptive network model for pain and pleasure through spicy food and its desensitization

This paper aims to map out the adaptive causal pathways of processes underlying capsaicin consumption and the desensitization process of the TRPV1 receptor as a feedback loop together with pain and pleasure perception. In order to map out these causal capsaicin pathways, adaptive causal network modeling was applied, which is a way of modeling biological, neural, mental and social processes from an adaptive causal modeling perspective.