| 甲状腺激素在脑发育中的作用及临床意义 |
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| 引用本文： | 陈俊荣,宋翠荣. 甲状腺激素在脑发育中的作用及临床意义[J]. 医学与哲学(人文社会医学版), 2008, 29(12): 47-48 |
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| 作者姓名： | 陈俊荣 宋翠荣 |
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| 作者单位： | 沧州医学高等专科学校,河北沧州061001 |
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| 摘 要： | 甲状腺激素在神经系统尤其是脑的发育和成熟过程中起着决定性的作用。甲状腺激素过多或过少直接关系到脑的发育和功能状况。有关甲状腺激素作用的分子机制的研究已经取得了重要的进步。研究发现发育脑中的甲状腺激素通过调控特异基因的表达来发挥作用。母体甲状腺激素主要影响妊娠前20周胎儿的神经发育。
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| 关 键 词： | 甲状腺激素 脑发育 分子机制 呆小病 |
The Effect and Clinical Significance of Thyroid Hormone in Brain Development |
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| CHEN Jun-rong,SONG Cui-rong. The Effect and Clinical Significance of Thyroid Hormone in Brain Development[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2008, 29(12): 47-48 |
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| Authors: | CHEN Jun-rong SONG Cui-rong |
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| Affiliation: | (. Cangzhou Medical College, Cangzhou 061001, China) |
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| Abstract: | Thyroid hormone has crucial impact on brain development and maturation. The concentration of the thyroid hormone is directly related to the development and function of brain. In recent years, the research on molecular mechanism of thyroid hormone in brain development has been a focus and obtained remarkable achievements. It reveals that thyroid hormone plays roles by regulating the expression of specific gene. In the first 20 weeks of gestation,neural development of the fetus is mostly dependent on thyroxin from the mother. |
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| Keywords: | thyroid hormone brain development molecular mechanism cretinism |
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