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慢性乙型肝炎抗病毒治疗的策略
引用本文:陈焕永,邵凤娟. 慢性乙型肝炎抗病毒治疗的策略[J]. 医学与哲学(人文社会医学版), 2008, 29(7): 20-21
作者姓名:陈焕永  邵凤娟
作者单位:哈尔滨医科大学附属第一医院感染科,黑龙江哈尔滨150001
摘    要:抗病毒治疗是慢性乙型肝炎治疗的关键,有效的抗乙型肝炎病毒药物主要有干扰素和核苷(酸)类似物。单药抗病毒治疗可获得较好的疗效,便于监测、管理;联合抗病毒治疗增加抗病毒疗效尚难肯定,更无法避免耐药发生,并可导致多药耐药、增加药物副作用和治疗费用。因此,优选单药进行抗病毒治疗才是目前理想的方案。

关 键 词:慢性乙型肝炎  抗病毒治疗  单药  干扰素  核苷(酸)类似物

Strategy of Antiviral Therapy of Chronic Hepatitis B
CHEN Huan-yong,SHAO Feng-juan. Strategy of Antiviral Therapy of Chronic Hepatitis B[J]. Medicine & Philosophy:Humanistic & Social Medicine Edition, 2008, 29(7): 20-21
Authors:CHEN Huan-yong  SHAO Feng-juan
Affiliation:(Department of Infectious Diseases ,the First Affiliated Hospital of Harbin Medical University, Harbin 150001 ,China)
Abstract:Antiviral therapy is the key therapy of chronic hepatitis B.Effective antiviral drugs for hepatitis B virus include interferon and nucleotide analogues. Single medication therapy can gain good effect and it is easy to monitor and manage. Combination therapy can not increase the efficiency and avoid the occurrence of resistance. Combination therapy maybe results in multi--resistance, increases adverse effects and expenses of therapy. Therefore single medication therapy is better.
Keywords:chronic hepatitis B  anti--virus therapy  single medication  interferon  nucleotide analogues
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