Failure of a peripheral muscle relaxant (suxomethonium bromide) to increase the efficacy of flooding (response prevention) in rats |
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| Authors: | M Baum S Roy R Leclerc |
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| Affiliation: | 1. Department of Civil and Environmental Engineering, University of Delaware, Newark, DE 19716, United States;2. Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, United States;3. Zachry Department of Civil and Environmental Engineering, Texas A&M University, College Station, TX 77843, United States;1. Department of Town & Country Planning, University of Moratuwa, Moratuwa, 10400, Sri Lanka;2. Urban Simulation Lab, Department of Town and Country Planning, University of Moratuwa, Moratuwa, 10400, Sri Lanka |
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| Abstract: | Rats were trained to avoid shock and then were given flooding in conjunction with a peripheral muscle relaxant, suxomethonium bromide. Control groups received injections of distilled water and/or the drug after flooding. The drug acted to change the spontaneous behaviour of the animals during flooding, but had no significant effect on the efficacy of flooding as evidenced in subsequent avoidance-extinction responding. Implications for the relaxation theory of flooding were discussed. |
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