| 肝移植患者的抗病毒治疗 |
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| 引用本文： | 王凤水.肝移植患者的抗病毒治疗[J].医学与哲学,2011(11):15-18,44. |
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| 作者姓名： | 王凤水 |
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| 作者单位： | 北京地坛医院,北京100011 |
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| 摘 要： | 乙肝相关性肝病肝移植患者术后乙型肝炎病毒再感染是影响其长期存活的主要因素，因此，有效地防治HBV再感染或者乙肝复发，是我国肝移植受者术后长期存活的关键。术前应用抗乙肝病毒药物，使血液中HBVDNA处于检测不到水平，以及术中使用高效价人乙肝免疫球蛋白，术后联合应用核苷类药物，保持抗-HBs水平大于100IU／L～150IU／L，可以达到长期有效预防HBV感染防止乙肝复发的目的。
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| 关 键 词： | 乙型肝炎 肝移植 复发 再感染 |
Antiviral Treatment of Patients of Liver Transplantation |
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| WANG Feng-shui.Antiviral Treatment of Patients of Liver Transplantation[J].Medicine & Philosophy:Humanistic & Social Medicine Edition,2011(11):15-18,44. |
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| Authors: | WANG Feng-shui |
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| Institution: | WANG Feng-shui. Beijing Ditan Hospital ,Beijing 100011 ,China |
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| Abstract: | Re-infection is the main factor affecting the long-term survival for Hepatitis B-related liver disease after liver transplantation（LT） in patients with hepatitis B Virus（HBV）. Therefore, effectively prevent and treat HBV re--infection or recurrence of hepatitis B is the key to a long--term survival for liver transplant recipients in China. Preoperative anti-- HBV drugs for the undetectable levels of HBV DNA in blood, and the intraoperative use of high titer of hepatitis B immunoglobulin （ HBIG）, and HBIG plus the same nucleotide drugs after LT to maintain anti-- HBs levels greater than 100-- 150 IU/L, can achieve the purpose for the long--term effective preventing HBV infection or hepatitis B recurrence. |
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| Keywords: | hepatitis B liver transplantation recurrence re--infection |
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