代谢综合征的争议与共识

代谢综合征（metabolic syndrome，MS）的主要组分包括中心性肥胖、高血压、糖耐量异常、脂代谢紊乱，而胰岛素抵抗被认为是MS的病理生理学基础。目前，对MS的认识还存在诸多争议，主要包括MS的命名、病因机制和病理生理学基础、其各组分及其阈值的确定以及对心血管疾病的预测价值。尽管存在争议，MS概念的提出将有助于对高危人群的心脑血管疾病及糖尿病的防治。

Controversies and Consensus Concerning Metabolic Syndrome

The main components of the metabolic syndrome （MS） are central obesity, hypertension, glucose intolerance and dyslipidemia, whereas the pathophysiology basis of MS seems to be attributable to insulin resistance. MS remains in dispute nowadays. The main disputes include： disputes over the denomination of MS, disputes over the pathogenesis mechanism and pathological basis of MS, disputes over the definition on the components and thresholds of MS, disputes over the values of MS in predicting cardiovascular disease. Despite these disputes, MS is a useful concept to prevent and treat the cardiocerebrovascular disease in high-risk group.