1. Department of Psychiatry, School of Medkine, Neuropsychiatrie Institute, University of California, 90024, Los Angeles, California 2. Veterans Administration Medical Center, 90073, Brentwood, Los Angeles, California
Abstract:
A smoke-mixing device is described that allows individuals to select their preferred nicotine deliveries from cigarette smoke on a puff-by-puff basis. This methodology offers advantages over previous strategies to investigate the role of nicotine as a reinforcing constituent of tobacco.