TIME RELATIONS OF OBJECTIVE AND SUBJECTIVE REACTIONS TO D-AMPHETAMINE AND PENTOBARBITONE |
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| Authors: | Marianne Frankenhaeuser Birgitta Post |
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| Institution: | Psychological Laboratory, University of Stockholm, and Laboratory of Aviation and Naval Medicine, Karolinska institutet, Stockholm, Sweden |
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| Abstract: | Successive measurements of pulse rate, blood pressure, objective and subjective reaction speed, and six mood variables were made on 12 healthy subjects during 135 min. periods following the intake of either 15 mg d-amphetamine, 200 mg Pentobarbitone, or a placebo. It was shown that (1) the two drugs had essentially opposite effects on all objective and most subjective variables; (2) after d-amphetamine subjective effects appeared earlier and reached their maximum more rapidly than objective effects; (3) both types of reaction were less pronounced after Pentobarbitone than after d-amphetamine under the present dose conditions; and that (4) after Pentobarbitone maximum objective effects were attained at an earlier point in time. |
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