Use of the conditional reflex to assess the temporal characteristics of curarization effects on heart rate responding |
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Authors: | Roger D. Ray |
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Affiliation: | 1. Department of Behavioral Science, Rollins College, Winter Park, Florida
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Abstract: | A Pavlovian methodological counterpart to the use of druginduced changes in operant rates of responding was used to assess the temporal characteristics of d-tubocurarine chloride effects on the heart rate conditional reflex in rats. After a stable conditional reflex had been established, the base heart rate, as well as the unconditional and conditional reflex, was monitored during administration of the drug. A sizable behavioral effect was reflected in all three measures, including a temporary abolition of the conditional and unconditional reflexes. An interpretation of these results was discussed, and further development and application of this specific methodology was explored. |
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