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Post-genomics, between reduction and emergence
Authors:Michel Morange
Institution:(1) Département de Biologie, Ecole Normale Supérieure, 46 rue d’Ulm, 75005 Paris, France
Abstract:It is frequently said that biology is emerging from a long phase of reductionism. It would be certainly more correct to say that biologists are abandoning a certain form of reductionism. We describe this past form, and the experiments which challenged the previous vision. To face the difficulties which were met, biologists use a series of concepts and metaphors - pleiotropy, tinkering, epigenetics - the ambiguity of which masks the difficulties, instead of solving them. In a similar way, the word “post-genomics” has different meanings, depending upon who uses it. Which of these meanings will become dominant in the future is an open question.
Keywords:Post-genomics  Emergence  Reductionism  Holism  Epigenetics  Tinkering
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