Low-noise microvolt level calibrator for measurement of performance of biosignal recording systems

A calibrator, the noise level of which is below the noise level generated in the preamplifier system, was needed for testing and development of a multichannel recording system. A multichannel preamplifier head assembly was used for recording cortical, subcortical, and cerebellar slow potentials and multiunit activity in freely moving cats and restrained rabbits. An inexpensive, battery-powered, lownoise voltage signal generator for calibration of the preamplifiers is described. The circuit provides a square-wave output at a frequency of 10 or 1000 Hz, and the peak-to-peak (p-p) amplitude can be selected at 10, 100, or 1000µV. The measured output noise of the calibrator is below 2µV (p-p, 0.1–6000 Hz). The frequency and amplitude values can be easily adapted for different purposes by changing a few component values. An amplified (gain 1,000×) test output for direct oscilloscope monitoring is included in the calibrator circuit.