Effect of unpleasant loud noise on hippocampal activities during picture encoding: an fMRI study |
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| Authors: | Hirano Yoshiyuki Fujita Masafumi Watanabe Kazuko Niwa Masami Takahashi Toru Kanematsu Masayuki Ido Yasushi Tomida Mihoko Onozuka Minoru |
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| Affiliation: | Department of Physiology and Neuroscience, Kanagawa Dental College, Yokosuka 238-8580, Japan. yosh-hir@qa2.so-net.ne.jp |
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| Abstract: | The functional link between the amygdala and hippocampus in humans has not been well documented. We examined the effect of unpleasant loud noise on hippocampal and amygdaloid activities during picture encoding by means of fMRI, and on the correct response in humans. The noise reduced activity in the hippocampus during picture encoding, decreased the correct response and increased the activity of the amygdala. A path diagram using structural equation modeling suggested that hippocampus activity might be depressed by high amygdala activity. Therefore, noise should diminish memory by reducing hippocampal activity, which might be depressed by high amygdala activity. |
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| Keywords: | Unpleasant Loud noise Encoding Amygdala Hippocampus Prefrontal area fMRI |
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