The lie scale as a predictor of placebo response

Patients engaged in a trial of mepriprazole on the irritable bowel syndromewere administered the Eysenck Personality Questionnaire and the Symptom Rating Test. It was hypothesized that high Lie scorers—‘lacking in insight’—would respond to treatment. There was little difference between the active drug and placebo but the results indicated that it was the low Lie scorers who showed improvement, and are interpreted in terms of a repression-sensitization dichotomy.