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Cognitive and affective predictors of treatment outcome in cognitive processing therapy and prolonged exposure for posttraumatic stress disorder
Authors:Shireen L Rizvi  Dawne S Vogt  Patricia A Resick
Institution:1. National Center for PTSD, VA Boston Healthcare System;2. Boston University School of Medicine;1. National Center for PTSD (Executive Division), White River Junction, VT and Geisel School of Medicine at Dartmouth, Hanover, NH, USA;2. Cincinnati VA Medical Center and University of Cincinnati, Cincinnati, OH, USA;3. National Center for PTSD (Dissemination and Training Division) and Stanford University School of Medicine, Palo Alto, CA, USA;4. VA Cooperative Studies Program Coordinating Center, Palo Alto, CA, USA;5. Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA;6. Duke University Medical School, Durham, NC, USA;7. University of Pennsylvania, Philadelphia, PA, USA;8. National Center for PTSD (Behavioral Science Division), Boston University School of Medicine, and VA Boston Healthcare System, Boston, MA, USA;9. Cooperative Studies Program Central Office, Department of Veterans Affairs Office of Research & Development, Washington, DC, USA
Abstract:This study examined cognitive and affective predictors of treatment dropout and treatment efficacy in Cognitive Processing Therapy (CPT) and Prolonged Exposure (PE) for PTSD. Study participants were women with PTSD from a sexual assault who received at least one session of either treatment (n = 145) as part of a randomized clinical trial. Results revealed that younger age, lower intelligence, and less education were associated with higher treatment dropout, whereas higher depression and guilt at pretreatment were associated with greater improvement in PTSD symptomatology. Results by treatment condition indicated that women with higher anger at pretreatment were more likely to dropout of PE and that older women in PE and younger women in CPT had the best overall outcomes. These findings have implications for efforts to enhance treatment efficacy and retention in CBT treatment protocols.
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