抗生素相关性腹泻的治疗与预防

抗生素相关性腹泻（antibiotic-associated diarrhea，AAD）指应用抗生素特别是广谱抗生素，导致肠道菌群失调或非肠道寄生菌的大量增生繁殖而造成的腹泻，为较常见的不良反应。约10％～25％的AAD和几乎所有的伪膜性肠炎均由难辨梭状芽孢杆菌引起。停用抗生素是最简单有效的措施，而合理应用抗生素才是预防AAD的关键。

The Treatment and Prevention of Antibiotic-associated Diarrhea

Antibiotic-associated diarrhea is reduced by alteration of intestinal flora or generous propagation of non-enteric parasitic bacterium after the use of antibiotic, especially broad-spectrum antibiotic, and it＇s a common adverse drug reaction. About 10 %-25 % of antibiotic-associated diarrhea and nearly all of the pseudomembranous enterocolitis are caused by clostridium difficile. Stop using antibiotic is the most simple and effective measure, while using antibiotic reasonably is the key point to prevent antibiotic-associated diarrhea.