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Methylphenidate-induced obsessive-compulsive symptoms in an elderly man
Authors:Serby Michael
Institution:Department of Psychiatry, Beth Israel Medical Center, and Albert Einstein College of Medicine, New York, New York 10003, USA. mserby@bethisraelny.org
Abstract:An 82-year-old man with treatment-resistant depression and early Alzheimer's disease was started on methylphenidate. Significant obsessive-compulsive behavior ensued but diminished over several weeks when methylphenidate was replaced by fluvoxamine. The patient had no prior psychiatric history, but he had a sister with obsessive-compulsive disorder. It appears that methylphenidate precipitated the patient's pathological behavior.
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