反社会人格障碍的神经生物学基础及其司法启示

反社会人格障碍(Antisocial Personality Disorder, ASPD)是一种漠视或侵犯他人权益的普遍行为模式, 是与犯罪关联极高的精神障碍。ASPD的形成受基因和环境因素的影响, 表现为神经递质和激素系统的紊乱, 以及自主神经系统活跃程度和大脑结构与功能的异常。上述神经生物学因素可能导致ASPD患者表现出执行控制障碍、情绪功能障碍、无视惩罚信息和奖赏偏好等特点。神经生物学研究的证据为ASPD罪犯的循证矫治、风险评估、定罪量刑等司法实践提供了启示。建议未来从神经生物学角度对ASPD的诊断分类标准、治疗方法和影响因素等方面开展研究。

The neurobiological evidence of antisocial personality disorder and its judicial implications

Antisocial Personality Disorder (ASPD) is a personality disorder with pervasive disregard for and violation of the rights of others accompanied with high crime propensity. The formation of ASPD is affected by genetic and environmental factors, manifested in abnormalities in neurotransmitter and hormonal system, autonomic nervous system and brain structure and function. To a certain degree, these neurobiological characteristics may cause ASPD to exhibit poor inhibitory control, emotional dysfunction, disregard of punishment and reward dominance. Neurobiological evidence provides judicial implications, such as treatment, risk assessment, conviction and sentencing of ASPD offenders. More research is needed on the diagnostic classification criteria, evidence based practice and influencing factors of ASPD from the perspective of neurobiology.