物质相关线索对成瘾者反应抑制的影响

成瘾者失控的物质寻求和使用与反应抑制的关系密切。很多研究在物质相关线索情境中探讨了这一关系。物质相关线索既可受到自动的注意加工, 又可诱发非自动的趋近动机状态。因此, 它们可能通过刺激驱动和状态依赖两种方式消耗有限的认知资源从而影响反应抑制, 这在成瘾行为的发展和维持中起到重要作用。未来需要在揭示其神经机制、明确物质使用动机或态度的调节、采用真实情境进行研究, 以及开发有效的干预方法等几个方面开展研究。

Effects of substance-related cues on response inhibition in addicts

Loss of control in substance seeking and use of addicts is closely related to response inhibition. Many studies have explored this relationship in context of substance-related cues. Substance cues can be automatically captured by attention and also induce non-automatic approach-motivated state. As a consequence, these cues may consume limited cognitive resources through a stimulus-driven and a state-dependent manner in order to influence addicts' response inhibition. And these effects also play important roles in the development and maintenance of addictive behaviors. Further research should be carried out to reveal the neural mechanisms of both manners, clarify how motivations and attitudes towards substance use modulate these effects, conduct research in real situations, and discover more effective interventions.