噻唑烷二酮类药物在1型糖尿病治疗中的价值 |
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引用本文: | 王安平,周智广. 噻唑烷二酮类药物在1型糖尿病治疗中的价值[J]. 医学与哲学(人文社会医学版), 2009, 0(12): 25-27 |
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作者姓名: | 王安平 周智广 |
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作者单位: | 中南大学湘雅二医院内分泌科,湖南长沙410011 |
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摘 要: | 噻唑烷二酮类药物(TZD)已在2型糖尿病中广泛应用。鉴于TZD具有增加胰岛素敏感性、抗炎症、调节免疫等作用,对它在1型糖尿病中的应用价值亦有探讨,这有助于指导实践和进一步研究。
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关 键 词: | 噻唑烷二酮类药物 1型糖尿病 β细胞 |
The Clinical Value of Thiazolidinediones in Type 1 Diabetes |
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Affiliation: | WANG An-ping, ZHOU Zhi- guang( Department of Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011 ,China) |
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Abstract: | The thiazolidinediones(TZDs), ligands for peroxisome proliferator-- activated recep-tor--gamma (PPAR--7), have been widely used in prevention and treatment of type Ⅱ diabetes. However, there is growing controversy whether TZDs have direct benefit on type Ⅰ diabetes or not. Rational evaluation for the clinical value of TZD on Type l diabetes is necessary for clinical application and for the further study. |
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Keywords: | Thiazolidinediones Type Ⅰ diabetes β cells |
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