Visual Imagery Processing and Knowledge of Famous Names in Alzheimer's Disease and MCI |
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Authors: | Céline Borg Catherine Thomas-Antérion Soline Bogey Karine Davier Bernard Laurent |
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Affiliation: | 1. Neurology/Neuropsychology-CMRR Unit , Saint Etienne, France celine.borg@univ-lyon2.fr;3. Neurology/Neuropsychology-CMRR Unit , Saint Etienne, France |
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Abstract: | ABSTRACT The study of memory for famous people and visual imagery retrieval was investigated in patients in the early stages of Alzheimer's disease (AD) and in the prodromal stage of AD, so-called Mild Cognitive Impairment (MCI). Fifteen patients with AD (MMSE ≥23), 15 patients with amnestic MCI (a-MCI) and 15 normal controls (NC) performed a famous names test designed to evaluate the semantic and distinctive physical features knowledge of famous persons. Results indicated that patients with AD and a-MCI generated significantly less physical features and semantic biographical knowledge about famous persons than did normal control participants. Additionally, significant differences were observed between a-MCI and AD patients in all tasks. The present findings confirm recent studies reporting semantic memory impairment in MCI. Moreover, the current findings show that mental imagery is lowered in a-MCI and AD and is likely related to the early semantic impairment. |
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Keywords: | Alzheimer's disease Mild Cognitive Impairment Famous names test Semantic knowledge Mental imagery |
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