The Relationship between Contrast Sensitivity,Gait, and Reading Speed in Parkinson's Disease

ABSTRACT

Parkinson's disease (PD) results in reduced walking speed and visual difficulties, including difficulty reading (Davidsdottir, Cronin-Golomb, & Lee, 2005 Davidsdottir, S., Cronin-Golomb, A. and Lee, A. 2005. Visual and spatial symptoms in Parkinson's disease. Vision Research, 45: 1285–1296. [Crossref] , [Google Scholar]). PD is characterized by a reduction in dopamine, which is instrumental in determining a person's contrast sensitivity (CS). This study assessed the relationship between CS, gait (step length and walking speed), and reading speed in 18 non-demented PD volunteers with normal acuity. We found that CS correlated with walking speed (r = .57, p = .01), step length (r = .53, p = .02), and reading speed (r = .54, p = .02). Visual acuity (which has not been tied to dopamine in the same way) correlated with reading speed (r_s = –.65, p = .004), but not with gait measures. We also assessed the contribution of age, education, and cognitive status (Shipley Institute of Living Scale) to these variables. We conclude that CS and age both play an important role in determining gait in PD, while reading speed is related to both acuity and CS, but not age.